| 摘要 |
The present invention relates to a genetic variant of CMV, said genetic variant lacking intron 2 of the IE region of CMV (CMV ???i2). The present invention also related to various uses of this genetic variant as well as RNA splice variants transcribed therefrom, and proteins expressed from the RNA splice variants, such as in the diagnosis of a CMV related cancer disease, and identification of individuals at risk of developing cancer or risk of transferring the CMV ???i2 virus with a human sample and prevention and treatment through targeting of unique CMV IE proteins for immunotherapy and vaccination. |
