发明名称 COMPOUNDS FOR USE IN THE TREATMENT OF PERIPHERAL NEUROPATHY
摘要 Benzodioxo compound (I) or its salt, is new. Benzodioxo compound of formula (I) or its salt, is new. A 1, A 2, A 3 : H, halo, or 1-4C alkyl group; R 1, R 2, R 3 : H, or 1-4C alkyl; Y 1 : -OH (preferred), (=O) or -SH; and n : 1 or 2. Independent claims are included for: (1) a pharmaceutical composition comprising (I) and at least an additional compound and/or at least one additional cytostatic or antimitotic compound and/or optionally in combination with a excipient; and (2) a products containing (I) and at least one additional compound and/or at least one additional cytostatic or antimitotic compound as a combination product for a simultaneous, separate or sequential use. [Image] - ACTIVITY : Neuroprotective; Antidiabetic; Antialcoholic; Nephrotropic. - MECHANISM OF ACTION : Gamma amino butyric acid receptor inhibitor; Cytochrome P1A2 isoenzyme inhibitor; Cytochrome P3A4 isoenzyme inhibitor.
申请公布号 PT2229943(E) 申请公布日期 2012.10.11
申请号 PT20100305260T 申请日期 2010.03.16
申请人 BIOCODEX 发明人 MARIE-EMMANUELLE LE GUERN;BERNARD HUBLOT;MARC VERLEYE;JEAN-MARIE GILLARDIN
分类号 A61K31/357;A61K31/36;A61K45/06;A61P25/02 主分类号 A61K31/357
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