摘要 |
<p>A compound represented by the following formula or a salt thereof, which has an GPR119 agonist action, is useful for the prophylaxis or treatment of diabetes, obesity and the like, and shows superior efficacy:
wherein
P: substituted 6-membered aromatic ring,
Q: (substituted) 6-membered aromatic ring,
A 1 : CR 4a R 4b , NR 4c , O, S, SO or SO 2 {R 4a-4c : H etc.},
L 1 : (substituted) C 1-5 alkylene,
L 2 : a bond or (substituted) C 1-3 alkylene,
L 3-4 : (substituted) C 1-3 alkylene,
R 1 : H, X, CN, (substituted) hydrocarbon, (substituted) heterocycle or (substituted) OH, or (substituted) 4- to 8-membered (heterocyclic) ring together with A 1 ,
R 2 : H, CN, (substituted) hydrocarbon, and
R 3a : -COSR A1 , (substituted) 5- or 6-membered aromatic ring {R A1 : (substituted) hydrocarbon or (substituted) heterocycle}.</p> |