| 摘要 |
<p>Pure bile acids are isolated from the bile of warm-or cold-blooded animals by treating the bile raw material, or a product obtained therefrom by mild alkaline hydrolysis or esterification, in a solvent system of is not2 phases in one phase of which the bile acids or their derivs. are soluble and the pigments and other impurities (or their derivs.) are insoluble and in the other phase(s) of which the bile acids or their derivs. are insoluble and the pigments and other impurities (or their derivs.) are soluble; separating the phases from each other. isolating the bile acids or their derivs. from the phase contg. them; and opt. subjecting to further purification steps. Process is simple and economical giving bile acids of >99% purity. Suitable bile starting material is that obtained from birds (giving 3alpha, 7alpha-dihydroxy-5beta-cholanic acid as main product) or fishes.</p> |
