| 发明名称 |
QUINAZOLINONES AS INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA |
| 摘要 |
Compounds that inhibit PI3Kδactivity, including compounds that selectively inhibit PI3Kδactivity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation in which PI3Kδplays a role in leukocyte function, using the compounds also are disclosed.
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| 申请公布号 |
US2012015964(A1) |
申请公布日期 |
2012.01.19 |
| 申请号 |
US201113163597 |
申请日期 |
2011.06.17 |
| 申请人 |
FOWLER KERRY W.;HUANG DANWEN;KESICKI EDWARD A.;OOI HUA CHEE;OLIVER AMY;RUAN FUQIANG;TREIBERG JENNIFER;ICOS CORPORATION |
发明人 |
FOWLER KERRY W.;HUANG DANWEN;KESICKI EDWARD A.;OOI HUA CHEE;OLIVER AMY;RUAN FUQIANG;TREIBERG JENNIFER |
| 分类号 |
A61K31/52;A61K31/517;A61K31/519;A61P35/00;A61P35/02;C07D239/91;C07D473/16;C07D473/34;C07D487/04;C12N5/09 |
主分类号 |
A61K31/52 |
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