发明名称 |
NANOSCALE PLATINUM COMPOUNDS AND METHODS OF USE THEREOF |
摘要 |
The invention is directed to biocompatible conjugated polymer nanoparticles including a copolymer backbone, a plurality of sidechains covalently linked to said backbone, and a plurality of platinum compounds dissociably linked to said backbone. The invention is also directed to dicarbonyl-lipid compounds wherein a platinum compound is dissociably linked to the dicarbonyl compound. The invention is also directed to methods of treating cancer or metastasis. The methods includes selecting a subject in need of treatment for cancer or metastasis and administering to the subject an effective amount of any of the nanoparticles, compounds, or compositions of the invention. |
申请公布号 |
EP2393854(A2) |
申请公布日期 |
2011.12.14 |
申请号 |
EP20100739130 |
申请日期 |
2010.02.04 |
申请人 |
THE BRIGHAM AND WOMEN'S HOSPITAL, INC. |
发明人 |
SENGUPTA, SHILADITYA;PARASKAR, ABHIMANYU;SONI, SHIVANI;SENGUPTA, POULOMI;BASU, SUDIPTA |
分类号 |
C08F222/06;A61K47/48;A61P35/00;C08F8/42;C08F22/06 |
主分类号 |
C08F222/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|