RADIOACTIVE GOLD NANOPARTICLES AND METHODS OF MAKING AND USING THEM
摘要
Methods of preparing a composition comprising non-ionic, radioactive gold nanoparticles (R-GNPs) are disclosed. The method comprises: a) providing an aqueous composition comprising gold (Au-197) ions in the absence of a template; and b) exposing the aqueous composition in the absence of the template to neutron irradiation to generate the composition comprising the non-ionic R-GNPs. Alternatively, the method comprises: a) providing an aqueous composition comprising gold (Au-197) nanoparticles (GNPs) in the absence of a template; and b) exposing the aqueous composition comprising the GNPs in the absence of the template to neutron irradiation and thereby generating the composition comprising the non-ionic R-GNPs. Compositions that comprises mesoporous silica nanoparticles (MSNs) and non-ionic R-GNPs encapsulated within pores and/or channels and further anchored to the surfaces of the MSNs, and methods of making the same are also disclosed.
申请公布号
EP2373450(A1)
申请公布日期
2011.10.12
申请号
EP20090796527
申请日期
2009.12.14
申请人
NATIONAL HEALTH RESEARCH INSTITUTES;NATIONAL TSING HUA UNIVERSITY