BIOMARKERS FOR PRE-SELECTION OF PATIENTS FOR ANTI-IGF1R THERAPY

摘要

PROBLEM TO BE SOLVED: To provide a method of identifying a specific cancer population and/or a specific cancer patient who is likely to be most responsive to one or more anti-cancer therapeutic agents which make IGF1R a target. SOLUTION: The present invention provides methods for identifying patients whose cancers are likely to be responsive to IGF1R inhibitory anti-cancer therapy along with methods for treating such patients. Patients identified by a method of the present invention can be treated with any of several known IGF1R inhibitory agents including antibodies, small molecule inhibitors and anti-sense nucleic acids. COPYRIGHT: (C)2011,JPO&INPIT