The present invention is directed to analogs of paromomycin having a variety of chemical functional groups attached at the 2"-O-positions as well as their preparation and use as propyylactic or therapeutics against microbial infection. (see formula I)
申请公布号
CA2585253(C)
申请公布日期
2011.05.24
申请号
CA20052585253
申请日期
2005.11.07
申请人
ISIS PHARMACEUTICALS, INC.
发明人
ADHIKARI, SUSANTA SEKHAR;MIGAWA, MICHAEL T.;GRIFFEY, RICHARD H.;SWAYZE, ERIC E.;PACHAMUTHU, KANDASAMY;HANESSIAN, STEPHEN;SZYCHOWSKI, JANEK