The invention relates to a method for determining prognosis of subjects with ovarian carcinoma using a biological sample comprising genomic tumor DNA isolated from the subject. According to the invention, the method comprises the steps of: determining the methylation status of a CpG dinucleotide in a target sequence that is selected from the group consisting of the target sequences as referred to by name in Table 1 in a biological sample isolated from a subject; and deducing from the determined methylation status of the target sequence the prognosis of subject with ovarian carcinoma. The improved prognosis determination of the subject with ovarian carcinoma enables the improved treatment of the said patient.
申请公布号
WO2011051414(A1)
申请公布日期
2011.05.05
申请号
WO2010EP66413
申请日期
2010.10.28
申请人
SIGNATURE DIAGNOSTICS AG;MODEL, FABIAN;RUJAN, TAMAS;MAYR, TOBIAS;ROSENTHAL, ANDRE
发明人
MODEL, FABIAN;RUJAN, TAMAS;MAYR, TOBIAS;ROSENTHAL, ANDRE