| 发明名称 |
Bone/joint disease susceptibility gene and use thereof |
| 摘要 |
The present invention provides the prophylaxis and treatment of bone and joint diseases by regulating the expression or activity of calmodulin, the prophylaxis and treatment of bone and joint diseases by regulating the expression or activity of asporin, and a diagnostic method for genetic susceptibility to bone and joint diseases by detecting polymorphisms in the CALM1 gene and/or the asporin gene, and the like.
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| 申请公布号 |
EP2311953(A1) |
申请公布日期 |
2011.04.20 |
| 申请号 |
EP20100181513 |
申请日期 |
2005.08.03 |
| 申请人 |
RIKEN;TAKEDA PHARMACEUTICAL COMPANY LIMITED |
发明人 |
IKEGAWA, SHIRO;KIZAWA, HIDEKI;MOTOTANI, HIDEYUKI |
| 分类号 |
C12N15/12;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P19/02;A61P19/08;A61P35/00;C07K14/47;C12Q1/68;G01N33/15;G01N33/50 |
主分类号 |
C12N15/12 |
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