发明名称 |
Enhanced clearance in an artificial kidney incorporating a pulsatile pump |
摘要 |
A continuous renal replacement therapy (CRRT) device is provided that weighs between 2 and 10 pounds. The CRRT device can be portable, mobile or completely worn on the person of the patient. Blood and dialysate are each pumped in a pulsed or pulsatile manner through a dialyzer such that a significant portion of the peak pulse of the blood flow coincides with a significant portion of a low pulse portion of the dialysate flow. An differential pressure between a dialysate inlet of the dialyzer and the blood inlet of the dialyzer periodically changes from a high differential pressure of between 70 and 120 mmHg for a first time period and a low differential pressure of between−10 and 10 mmHg for a second time period. The frequency of the high and low differential pressure cycle is between about 0.5 and 4 Hz. |
申请公布号 |
US7871390(B2) |
申请公布日期 |
2011.01.18 |
申请号 |
US20070942626 |
申请日期 |
2007.11.19 |
申请人 |
FRESENIUS MEDICAL CARE HOLDINGS, INC. |
发明人 |
RAMBOD EDMOND;GURA VICTOR |
分类号 |
A61M37/00;C02F1/44 |
主分类号 |
A61M37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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