发明名称 |
NOVEL MONOCLONAL ANTIBODY AND USE OF THE SAME |
摘要 |
<p>The present invention provides an anti-PAC1 monoclonal antibody capable of recognizing a PAC1 having a native structure, a PAC1 activity regulator (in particular, activity inhibitor) containing the antibody, a prophylactic/therapeutic agent for a disease associated with accentuation of a bioactivity of PAC1, containing the antibody, a diagnostic reagent for a disease associated with an abnormality of PAC1 activity, containing the antibody, and a screening method for a substance that regulates the expression of PAC1, using the antibody and a PAC1-expressing cell.</p> |
申请公布号 |
EP2048162(A4) |
申请公布日期 |
2010.12.01 |
申请号 |
EP20070805903 |
申请日期 |
2007.08.07 |
申请人 |
PRESIDENT, KYOTO UNIVERSITY;TAKEDA PHARMACEUTICAL COMPANY LIMITED |
发明人 |
SHIRAKAWA, MASAHIRO;INOOKA, HIROSHI |
分类号 |
C07K16/28;A61K39/395;A61P3/10;A61P5/48;A61P15/00;A61P25/02;A61P25/18;A61P25/24;A61P43/00;C12N15/09;C12P21/08;C12Q1/02;C40B30/06;G01N33/15;G01N33/50;G01N33/53 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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