发明名称 |
Inhibitors of Integrin Alpha2Beta1 Based on Prolyl Diaminopropionic Acid Scaffold |
摘要 |
Novel compounds inhibiting the integrinα2β1/GPIa-IIa receptor are disclosed. Also disclosed are pharmaceutical compositions containing the compounds, as well as methods of their therapeutic use. The compounds disclosed are useful, inter alia, as inhibitors of integrinα2β1/GPIa-IIa-mediated activity.
|
申请公布号 |
US2010179119(A1) |
申请公布日期 |
2010.07.15 |
申请号 |
US20090566162 |
申请日期 |
2009.09.24 |
申请人 |
DEGRADO WILLIAM F;MILLER MEREDITH W;BASRA SANDEEP;BENNETT JOEL S;CHOI SUNGWOOK |
发明人 |
DEGRADO WILLIAM F.;MILLER MEREDITH W.;BASRA SANDEEP;BENNETT JOEL S.;CHOI SUNGWOOK |
分类号 |
A61K31/40;A61K31/397;A61K31/421;A61K31/426;A61K31/445;A61K31/47;A61K31/472;A61P3/10;A61P9/00;A61P9/10;A61P31/12;A61P35/00;C07D207/16;C07D211/60;C07D215/48;C07D217/26;C07D263/06;C07D277/06 |
主分类号 |
A61K31/40 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|