COMBINATION PRODUCT OF SPIRONOLACTONE AND DOXYCYCLINE

摘要

The present invention provides a pharmaceutical composition comprising a combination of an anti-androgen agent and an antibiotic/anti-inflammatory agent or pharmaceutically acceptable salts thereof, useful for treating a subject with a dermatological disorder. The combination of this invention preferably provides a synergistic effect in treating a subject with a dermatological disorder, specifically a subject with acne. In a preferred embodiment, the present invention provides a pharmaceutical composition comprising combination of spironolactone and doxycycline or pharmaceutically acceptable salts or hydrates thereof.