| 摘要 |
NEW MATERIAL:A compound (salt) expressed by formula I [R1 and R2 represent alkyl, aralkyl or aryl; X represents CO or formula II (R3 represents H, halogen atom or aryl); Y represents formula III (R represents aryl; R4 represents alkyl, aryl, H, etc.), etc.]. EXAMPLE:5,6-Dimethyl-1,3-diphenyl-1H-pyrazolo [ 3,4-d ]pyridazine-4,7(5H, 6H)-di one. USE:An anti-inflammatory agent and remedy for rheumatism. PREPARATION:For example, a compound expressed by formula IV (Z represents halogen atom) [example; 4-bromo-1,2-dimethylpyridazine-3,6(1H,2H)-dione, etc.] and a hydrazine derivative expressed by formula V (example; alpha- chlorobenzylidenephenylhydrazine, etc.) are suspended in dried benzene and triethylamine is dripped thereinto the carry out reaction and afford the com pound expressed by formula I.
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