摘要 |
The present invention provides a compound represented by the following Formula: wherein A is an aryl group or a heteroaryl group, each of which may be substituted; R<SUP>1 </SUP>is a group which is bonded through carbon; R<SUP>2 </SUP>is hydrogen or an aliphatic hydrocarbon group; and X is -NR<SUP>3</SUP>-, -O-, -S-, -SO-, -SO<SUB>2</SUB>-, or -CHR<SUP>3</SUP>- (wherein R<SUP>3 </SUP>is hydrogen or an aliphatic hydrocarbon group), or a salt thereof, or a prodrug thereof, which has growth factor receptor tyrosine kinase inhibitory activity and low toxicity, and is useful for prevention and treatment of cancer, and thus can be sufficiently used as a medicine.
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