发明名称 |
COMPOSITIONS AND METHODS FOR MODULATING AN IMMUNE RESPONSE |
摘要 |
<p>The present invention provides a composition for suppressing an inflammatory immune response comprising the excretory/secretory (ES) component of Fasciola hepatica or a fraction thereof. The composition has particular utility in the treatment or prophylaxis of T cell mediated inflammatory immune responses, and in particular autoimmune disease. The invention further extends to methods for modulating a T cell mediated immune response wherein a therapeutically effective amount of the excretory/secretory (ES) component from Fasciola hepatica is administered to a subject in need of such treatment in order to suppress the development of the response.</p> |
申请公布号 |
EP1962872(A2) |
申请公布日期 |
2008.09.03 |
申请号 |
EP20060821545 |
申请日期 |
2006.12.05 |
申请人 |
THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN |
发明人 |
MILLS, KINGSTON;BRADY, MIRIAM |
分类号 |
A61K35/56 |
主分类号 |
A61K35/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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