MEDICAL PRODUCT AND METHOD OF RHEUMATIC DISEASES TREATMENT

摘要

FIELD: medicine; rheumatology. ^ SUBSTANCE: preparation includes 0.1-3.0 mass % of methotrexate within phospholipid nanoparticles. Nanoparticles consist of phospholipids, glycyrrhizic acid or its salt and adjuvants. The total content of phospholipids and glycyrrhizic acid and its salts is 2-80 mass %. Mass ratio of phospholipids and glycyrrhizic acid or its salts is no more 4:1. Invention also concerns method of rheumatic diseases treatment by means of specified preparation. ^ EFFECT: decrease in preparation by-effects and maintenance of its therapeutic potential for rheumatic diseases treatment. ^ 4 cl, 3 dwg, 1 tbl, 1 ex