发明名称 REKOMBINANTE LEICHTE KETTE DES BOTOLINUM NEUROTOXINS AND FUSIONSPROTEINE DAVON ZUR VERWENDUNG IN FORSCHUNG UND KLINISCHER THERAPIE
摘要 The present invention relates to the construction, expression, and purification of synthetic or recombinant light chain (LC) botulinum neurotoxin genes from all botulinum neurotoxin serotypes. The methods of the invention can provide 1.1 g of the LC per liter of culture. The LC product is stable and proteolytically active. Methods of using the products of the invention are described.
申请公布号 DE60130266(D1) 申请公布日期 2007.10.11
申请号 DE2001630266 申请日期 2001.11.06
申请人 U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND 发明人 SMITH, LEONARD A.;JENSEN, MELODY
分类号 C07K14/33;C12N9/64 主分类号 C07K14/33
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