| 发明名称 |
COMPOSITIONS AND METHODS FOR MODULATING C-REL-DEPENDENT CYTOKINE PRODUCTION |
| 摘要 |
<p>The present invention is directed to compositions and methods for modulating c-Rel-dependent cytokine production without materially altering the level of expression of NFκB and/or the amount of IκB. The present invention is also directed to screening for modulators of c-Rel activity as determined by assaying for altered subcellular localization of c-Rel but where the level of expression of NFκB and/or the amount of IκB is materially unaltered.</p> |
| 申请公布号 |
EP1682682(A4) |
申请公布日期 |
2007.03.21 |
| 申请号 |
EP20040811092 |
申请日期 |
2004.11.10 |
| 申请人 |
SYNTA PHARMACEUTICALS CORPORATION |
发明人 |
LU, RONGZHEN;BARSOUM, JAMES;WADA, YUMIKO |
| 分类号 |
C12Q1/68;A61K;A61K48/00;C12N15/85;G01N33/50;G01N33/53;G01N33/567;G01N33/68 |
主分类号 |
C12Q1/68 |
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