发明名称 Novel pyridine derivative and pyrimidine derivative (3)
摘要 A compound represented by the following formula, a salt thereof or a hydrate of the foregoing has an excellent hepatocyte growth factor receptor (HGFR) inhibitory activity, and exhibits anti-tumor activity, angiogenesis inhibitory activity and cancer metastasis inhibitory activity. [R 1 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; R 2 and R 3 represent hydrogen; R 4 , R 5 , R 6 , and R 7 may be the same or different and each represents hydrogen, halogen, C 1-6 alkyl or the like; R 8 represents hydrogen or the like; R 9 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; n represents an integer of 1 or 2; X represents -CH=, nitrogen or the like.]
申请公布号 AU2006282456(A1) 申请公布日期 2007.03.01
申请号 AU20060282456 申请日期 2006.08.21
申请人 EISAI R & D MANAGEMENT CO., LTD. 发明人 HIROSHI OBAISHI;KEIKO TAKAHASHI;SHUJI SHIROTORI;SETSUO FUNASAKA;TOMOHIRO MATSUSHIMA
分类号 C07D213/75;A61K31/4409;A61K31/496;A61K31/506;A61K31/5377;A61P35/00;A61P35/04;A61P43/00;C07D239/47;C07D401/12 主分类号 C07D213/75
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