发明名称 Apparatus and system having dry gene silencing compositions
摘要 A reverse transfection apparatus can be used for introducing siRNA into a ce ll to effect gene silencing. Such an apparatus can include a well plate having a well configured for transfecting cells. The well can include a substantially dry gene silencing composition that has at least a first siRNA which silence s a first target gene. The gene silencing composition can be configured such that the at least first siRNA is capable of being solubilized or suspended i n an aqueous medium in an amount sufficient for transfecting cells in the well . Additionally, the at least first siRNA can include a modification or a conjugate. The reverse transfection apparatus can be provided as a kit or system that additionally includes cells, polynucleotide carriers, reverse transfection reagents, and the like.
申请公布号 AU2005322468(A2) 申请公布日期 2006.07.06
申请号 AU20050322468 申请日期 2005.11.21
申请人 DHARMACON, INC. 发明人 ANASTASIA KHVOROVA;WILLIAM S. MARSHALL;BARBARA ROBERTSON;KATHRYN ROBINSON;DEVIN LEAKE
分类号 C12N15/63;C07H21/02;C07H21/04;C12N15/00;C12N15/85;C12N15/87;C12Q1/68 主分类号 C12N15/63
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