BIOSENSOR CALIBRATION METHOD

摘要

PROBLEM TO BE SOLVED: To provide a technique for stably performing zero-point calibration and full-scale (span) calibration in a short period of time in a biosensor for detecting hazardous substances in environmental water, and also to provide a technique for performing zero-point calibration and full-scale (span) calibration in the normal state of water monitoring.

SOLUTION: The temperature of a mixture of water to be inspected and a substrate for the biosensor is held within a temperature range maintaining the correlation between oxygen consumption rates of the water to be inspected and liquid temperatures and reversibility. An output value of a dissolved oxygen sensor when the oxygen consumption rate is in a maximum state is stored. The stored output value is taken as a zero-point calibration value of the biosensor. On the basis of a measured value when the water to be inspected is in a state held at a low temperature, a differential value between a value computed from the value and the zero-point calibration value is computed. The differential value is taken as a range of measurement to determine the size of a span.

COPYRIGHT: (C)2006,JPO&NCIPI