Glycoproteins produced in plants with suppressed expression of beta 1, 2-xylosyltransferase

摘要

Recombinant glycoproteins, obtainable by a method wherein the recombinant glycoproteins are expressed in plants or in cells, wherein the expression of ²1, 2-xylosyltranferase is suppressed or completely blocked so that the peptide sequence of the glycoprotein has less than 50%, particulary less than 20%, particularly 0% of ²1, 2-bound xylose residues present in proteins expressed in non-xylosyl-transferase reduced plant systems.
Preferably, said recombinant glycoprotein is characterized in that it is a human protein, especially a human protein for medical use.