摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for separating chiral compounds by using a micelle electrodynamic capillary chromatography. <P>SOLUTION: This method of chiral separation is provided by bringing the chiral compound in contact with a chiral surfactant expressed by the general formula (wherein, R<SB>1</SB>=a 4-18C alkyl, a 4-18C halogen-substituted alkyl, a 4-18C polyether hydrocarbon, a 4-18C alkyl having a chiral center, in which the above alkyl groups may have unsaturated bond, or a cholesterol hydrocarbon; Y =CH<SB>2</SB>; A=NH; X=CO; C=carbon: Z=COO<SP>-</SP>, SO<SB>4</SB><SP>-</SP>, SO<SB>3</SB><SP>-</SP>, PO<SB>3</SB><SP>-</SP>, PO<SB>4</SB><SP>-</SP>, NR'<SB>3</SB><SP>+</SP>, PR'<SB>3</SB><SP>+</SP>, OH, a polyether, an ampho-ion or a polyalcohol; and R'=H or a 1-4C hydrocarbon and may be halogenated or may have unsaturated bond) of an effective amount under a condition of an electrophoretic capillary chromatography. <P>COPYRIGHT: (C)2005,JPO&NCIPI |