发明名称 |
Process for the production of amorphous atorvastatin calcium |
摘要 |
<p>A process for the preparation of amorphous atorvastatin calcium and hydrates thereof which comprises: (a) dissolving crystalline atorvastatin calcium in a non-hydroxylic solvent; (b) adding a non-polar hydrocarbon anti-solvent or adding the dissolved atorvastatin to the non-polar anti-solvent to precipitate out atorvastatin calcium; and (c) removing the solvent by filtration to afford amorphous atorvastatin calcium.</p> |
申请公布号 |
AU778962(B2) |
申请公布日期 |
2004.12.23 |
申请号 |
AU20000019967 |
申请日期 |
2000.01.06 |
申请人 |
RANBAXY LABORATORIES LIMITED |
发明人 |
YATENDRA KUMAR;RAJESH KUMAR THAPER;S.M. DILEEP KUMAR |
分类号 |
C07D207/34;(IPC1-7):A61K31/40 |
主分类号 |
C07D207/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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