| 发明名称 |
Pyridine derivatives with IKB-kinase (IKK-beta) inhibiting activity |
| 摘要 |
Pyridine derivative compounds of formula (I) with IkB kinase b (IKK-b) inhibiting activity are disclosed, wherein R1, R2, R3, R4 and R5 are as defined in the specification. These compounds have an excellent anti-inflammatory activity, and other biological activity wherein they can be used as an immunosuppressant, an agent to treat ischemia, an anti-tumoral agent, an agent for treating asthma etc.
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| 申请公布号 |
NZ524811(A) |
申请公布日期 |
2004.10.29 |
| 申请号 |
NZ20010524811 |
申请日期 |
2001.09.10 |
| 申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
MURATA, TOSHIKI;UMEDA, MASAOMI;SAKAKIBARA, SACHIKO;YOSHINO, TAKASHI;SATO, HIROKI;MASUDA, TSUTOMU;KORIYAMA, YUJI;SHIMADA, MITSUYUKI;SHINTANI, TAKUYA;KADONO, HIROSHI;ZIEGELBAUER, KARL B;FUCHIKAMI, KINJI;KOMURA, HIROSHI;LOWINGER, TIMOTHY B |
| 分类号 |
A61K31/437;A61K31/4375;A61K31/4418;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4545;A61K31/4709;A61K31/496;A61K31/519;A61K31/5365;A61K31/551;A61P1/04;A61P9/10;A61P11/02;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P19/06;A61P21/00;A61P27/02;A61P29/00;A61P31/00;A61P35/00;A61P37/02;A61P37/06;A61P43/00;C07D213/08;C07D213/09;C07D213/10;C07D213/73;C07D213/80;C07D213/85;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D405/14;C07D409/12;C07D409/14;C07D413/14;C07D471/04;C07D471/18;C07D498/04;C07D513/04;C07D521/00;(IPC1-7):C07D401/04;A61K31/442;A61K31/435 |
主分类号 |
A61K31/437 |
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