THE SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS

摘要

An outbreak of a virulent respiratory virus, now known as Severe Acute Respiratory Syndrome (SARS), was identified in Hong Kong, China and a growin g number of countries around the world in 2003. The invention relates to nucle ic acids and proteins from the SARS coronavirus. These nucleic acids and protei ns can be used in the preparation and manufacture of vaccine formulations, diagnostic reagents, kits, etc. The invention also provides methods for treating SARS by administering small molecule antiviral compounds, as well a s methods of identifying potent small molecules for the treatment of SARS.