发明名称 ALPHA-FETOPROTEIN IMMU31 ANTIBODIES AND FUSION PROTEINS AND METHODS OF USE THEREOF
摘要 The present invention provides humanized, chimeric and human anti-alpha- fetoprotein antibodies, fusion proteins, and fragments thereof. The antibodies, fusion proteins, and fragments thereof, as well as combinations with other suitable antibodies, are useful for the treatment and diagnosis o f hepatocellular carcinoma, hepatoblastoma, germ cell tumors carcinoma and oth er AFP-producing tumors.
申请公布号 CA2494310(A1) 申请公布日期 2004.02.12
申请号 CA20032494310 申请日期 2003.08.01
申请人 IMMUNOMEDICS, INC. 发明人 QU, ZHENGXING;HANSEN, HANS J.;GOLDENBERG, DAVID M.
分类号 A61K41/00;A61K47/48;A61K49/00;A61K51/10;A61P35/00;C07K16/18;C07K16/30;C12N15/13;G01N33/574;G01N33/68;(IPC1-7):C12N15/13;C12N5/10;A61K49/16;A61K39/395;C07K16/46;C12N15/62 主分类号 A61K41/00
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