发明名称 |
METHODS FOR PRODUCING EX VIVO MODELS FOR INFLAMMATORY DISEASE AND USES THEREOF |
摘要 |
The present invention relates to methods for inducing a pro-asthma/pro- inflammatory like state in a resident tissue cell, comprising contacting the cell with IL-1.beta., TNF.alpha. or both. Methods are also disclosed for identifying genes that regulate responses to anti-inflammatory drugs, to methods for drug screening, and to methods for identifying genes that correlate with various pro-asthma/pro-inflammatory disease phenotypes.</SDOA B>
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申请公布号 |
CA2459729(A1) |
申请公布日期 |
2003.03.20 |
申请号 |
CA20022459729 |
申请日期 |
2002.09.04 |
申请人 |
DECODE GENETICS EHF.;THE CHILDREN'S HOSPITAL OF PHILADELPHIA |
发明人 |
GRUNSTEIN, MICHAEL M.;HAKONARSON, HAKON |
分类号 |
C12Q1/68;G01N33/564;(IPC1-7):C12Q1/02;C12N5/00;C12Q1/04;C12N5/10;G01N33/53;G01N33/567 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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