发明名称 |
Duplex probes for hybridization reactions |
摘要 |
Methods are provide for quantitatively determining the amount of polynucleotides in a sample. In one method, the distinct polynucleotide targets and standard polynucleotide targets are contacted with detectable probes and independently detectable single or double stranded complements to the standard targets under hybridization conditions. The hybridization pattern from the probe is compared to the hybridization pattern from the standard sequences to obtain quantitative information about the genetic profile of the labeled nucleic acid sample. Also provided are kits for the use of the methods.
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申请公布号 |
US6448013(B1) |
申请公布日期 |
2002.09.10 |
申请号 |
US20000721801 |
申请日期 |
2000.11.22 |
申请人 |
INCYTE GENOMICS, INC. |
发明人 |
ARNOLD LYLE;BEDILION TOD;BIELDANES ERIK;THERIAULT THOMAS P.;LEI WARREN |
分类号 |
C12N15/09;C12Q1/68;(IPC1-7):C12Q1/68;C12P19/34;G01N33/00;C07H21/02;C07H21/04 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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