SPECIFIC AUTOIMMUNE REACTIONS AGAINST ISOMERISED/OPTICALLY INVERTED EPITOPES: APPLICATION FOR TREATMENT OF AUTOIMMUNE DISEASES
摘要
Methods and compositions for therapeutic or prophylactic treatment of an autoimmune disease by the selective suppression of autoimmune activity against an auto-antigen, which activity involves immunological reactivity with an epitope containing an isomerised peptide linkage and/or an optically inverted amino acid comprise the use of a protein or peptide or analogue thereof containing an epitope recognised by an auto-reactive immune system component involved in said condition, which epitope contains an isomerised peptide linkage and/or an optically inverted amino acid or comprising a compound which immunologically mimics a said protein or peptide.
申请公布号
WO0213844(A3)
申请公布日期
2002.05.30
申请号
WO2001EP09205
申请日期
2001.08.09
申请人
OSTEOMETER BIOTECH A/S;CLOOS, PAUL, ANDREAS, COMPARE;CHRISTGAU, STEPHAN