发明名称 PROCESS FOR PREPARING (+-)-CIS, TRANS-2-(DIMETHYLAMINO)-METHYL-1-(M-METHOXYPHENYL)CYCL OHEXANE-1-OL HYDROCHLORIDE
摘要 The invention relates to a process for preparing the (+-)cis, trans-2-(dimethylamino)-methyl-1-(m-methoxyphenyl)-cyclohexane-1-ol hydrochloride, consisting in neutralizing the corresponding base with a solution of chlorine hydride concentrated in n-propyl carbinol, with further azeotropic removal of water, the excess of n-propyl carbinol and chlorine hydride, the resulting product being then isolated by precipitation from anhydrous solvents.
申请公布号 RO117373(B) 申请公布日期 2002.02.28
申请号 RO19980000614 申请日期 1998.02.27
申请人 INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE CHIMICO-FARMACEUTICA - ICCF, BUCURESTI 发明人 ILIE CORINA;GUTA RODICA;ANDREESCU DOINA;TUDOR SIMONA;RADUCANU AURELIA;ROGOZEA ION
分类号 C07C213/10;(IPC1-7):C07C213/10 主分类号 C07C213/10
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