发明名称 |
PROCESS FOR PREPARING (+-)-CIS, TRANS-2-(DIMETHYLAMINO)-METHYL-1-(M-METHOXYPHENYL)CYCL OHEXANE-1-OL HYDROCHLORIDE |
摘要 |
The invention relates to a process for preparing the (+-)cis, trans-2-(dimethylamino)-methyl-1-(m-methoxyphenyl)-cyclohexane-1-ol hydrochloride, consisting in neutralizing the corresponding base with a solution of chlorine hydride concentrated in n-propyl carbinol, with further azeotropic removal of water, the excess of n-propyl carbinol and chlorine hydride, the resulting product being then isolated by precipitation from anhydrous solvents.
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申请公布号 |
RO117373(B) |
申请公布日期 |
2002.02.28 |
申请号 |
RO19980000614 |
申请日期 |
1998.02.27 |
申请人 |
INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE CHIMICO-FARMACEUTICA - ICCF, BUCURESTI |
发明人 |
ILIE CORINA;GUTA RODICA;ANDREESCU DOINA;TUDOR SIMONA;RADUCANU AURELIA;ROGOZEA ION |
分类号 |
C07C213/10;(IPC1-7):C07C213/10 |
主分类号 |
C07C213/10 |
代理机构 |
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