发明名称 FUSED BICYCLIC AMIDE COMPOUNDS AND MEDICINAL USE THEREOF
摘要 Compounds represented by the following general formula (I) wherein the ring A represents benzene, cyclohexane, pyridine, piperidine, a derivative thereof, imidazole, a derivative thereof, etc.; the ring B represents benzene, cyclohexane, pyrrole, a derivative thereof, furan, thiophene, etc.; R<1>, R<2> and R<3> represent each hydrogen, alkyl, halogeno, hydroxy, alkoxy, etc.; W represents hydrogen, alkyl or hydroxycarbonylalkyl; X represents halogeno, cyano, nitro, etc.; X' represents hydrogen, halogeno, etc.; and Y represents alkyl, hydroxyalkyl, hydroxycarbonylalkyl, aminoalkyl, etc.; salts thereof and drugs comprising these compounds. Because of having an excellent effect of inhibiting activated lymphocyte proliferation, these compounds are useful as preventives or remedies for various autoimmune diseases.
申请公布号 WO0212189(A1) 申请公布日期 2002.02.14
申请号 WO2001JP06852 申请日期 2001.08.09
申请人 WELFIDE CORPORATION;USHIO, HIROYUKI;NAITO, YOUICHIRO;SUGIYAMA, NAOKI;KAWAGUCHI, TAKAFUMI;OHTSUKI, MAKIO;CHIBA, KENJI 发明人 USHIO, HIROYUKI;NAITO, YOUICHIRO;SUGIYAMA, NAOKI;KAWAGUCHI, TAKAFUMI;OHTSUKI, MAKIO;CHIBA, KENJI
分类号 A61K31/015;A61K31/343;A61K31/381;A61K31/404;A61K31/4184;A61K31/4365;A61K31/4704;A61K31/498;A61P29/00;A61P37/00;A61P43/00;C07D209/42;C07D211/46;C07D307/85;C07D307/86;C07D333/70;C07D405/12;C07D409/12;C07D495/04 主分类号 A61K31/015
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