发明名称 Method for stabilising particle size distribution of a powdery active principle dispersed in a liquid and uses thereof
摘要 The invention concerns a method for stabilising particle size distribution of a powdery active principle, when the latter is dispersed in a liquid. Said method is characterised in that it consists in dispersing said active principle in a glycol ether or a mixture of glycol ethers. The invention also concerns the uses of said method and, in particular for pharmaceutical compositions and galenic forms comprising a retinoid as active principle, and suited for providing the latter with improved bioavailability (suprabioavailability) after oral administration.
申请公布号 AU5232001(A) 申请公布日期 2001.10.23
申请号 AU20010052320 申请日期 2001.04.11
申请人 CLL PHARMA 发明人 RENE GIMET;CLAUDE LARUELLE;DOMINIQUE TOSELLI
分类号 A61K9/16;A61K9/48;A61K31/203 主分类号 A61K9/16
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