发明名称 Substituted pyridine arylpiperazines usable for treating benign hyperplasia of prostate
摘要 <p>This invention relates a to a series of heterocyclic substituted piperazines of Formula Imethods of treatment, pharmaceutical compositions containing them, and intermediates used in their manufacture. The compounds of the invention selectively inhibit binding to the alpha-1a adrenergic receptor, a receptor which has been implicated in benign prostatic hyperplasia. As such the compounds are potentially useful in the treatment of this disease.</p>
申请公布号 CZ20003044(A3) 申请公布日期 2001.04.11
申请号 CZ20000003044 申请日期 1999.02.19
申请人 ORTHO-MCNEIL PHARMACEUTICAL, INC. 发明人 KUO GEE-HONG;MURRAY WILLIAM V.;PROUTY CATHERINE P.
分类号 A61K31/497;A61P13/08;A61P43/00;C07D213/82;(IPC1-7):C07D213/82;A61P15/00;A61K31/495 主分类号 A61K31/497
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