发明名称 PROCESS FOR PREPARING IMMUNOGENIC CONJUGATES
摘要 The invention relates to a process for preparing immunogenic conjugates, consisting of the quick addition of an aqueous solution comprising 1.15 parts of bovine serum albumin, at a temperature of 4 degree C, to 0.221 parts of an organo-chlorinated pesticide comprising an acid group and an aromatic ring for the activation of the carboxyl group, said mixture being left to rest for 20 hours, at a temperature of 4 degree C, and further centrifuged at 3,000 rpm for 30 min, the resulting precipitate being further dialysed four times, for 72 hours, with a solution 1 : 2 v/v of dioxan : water and vacuum dried, the parts being expressed by weight. The employed pesticides are: 2,4-dichlorophenoxy-acetic acid and 2-methoxy-3,6-dichlorobenzoic acid.
申请公布号 RO116460(B1) 申请公布日期 2001.02.28
申请号 RO19940001349 申请日期 1994.08.09
申请人 INSTITUTUL DE FIZICA SI INGINERIE NUCLEARA BUCURESTI-MAGURELE , BUCURESTI-MAGURELE 发明人 DOROBANTU IOAN;COTARLEA MONICA-IONELA
分类号 A61K39/39;(IPC1-7):A61K39/39 主分类号 A61K39/39
代理机构 代理人
主权项
地址