发明名称 Transforming growth factor alpha H1
摘要 <p>Disclosed is a human TGF- alpha -H1 polypeptide and DNA (RNA) encoding such TGF- alpha -H1 polypeptides. Also provided is a procedure for producing such polypeptide by recombinant techniques and for producing antibodies and antagonists against such polypeptide. Such polypeptides may be combined with a suitable pharmaceutical carrier or diluent to provide diagnostic, therapeutic and/or prophylactic effects against various diseases. Also provided are methods of using the antibodies and antagonists to inhibit TGF- alpha -H1 for therapeutic purposes.</p>
申请公布号 EP1063293(A2) 申请公布日期 2000.12.27
申请号 EP20000120470 申请日期 1994.05.12
申请人 HUMAN GENOME SCIENCES, INC. 发明人 MEISSNER, PAUL;FULDNER, REBECCA;ADAMS, MARK D.
分类号 G01N33/53;A61K31/70;A61K38/00;A61K38/27;A61K38/55;A61K39/395;A61K48/00;A61P1/16;A61P13/02;A61P15/00;A61P27/02;A61P35/00;A61P43/00;C07H21/04;C07K14/495;C07K16/22;C12N1/21;C12N15/09;C12N15/12;C12P21/08;C12R1/19;(IPC1-7):C12N15/12;G01N33/566;C12Q1/68;C12N15/11 主分类号 G01N33/53
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