发明名称 MESYLATE DIHYDRATE SALTS OF 5-(2-(4-(1,2-BENZISOTHIAZOL-3-YL)-1-PIPERAZINYL)-ETHYL)-6-CHLORO-1,3-DIHYDRO-2(1H)-INDOL-2-ONE, FARMACEUTICAL COMPOSITION AND METHOD OF TREATING A PSYCHOTIC DISORDER
摘要 1. A mesylate dihydrate salt of 5-(2-(4-(1 ,2-benzisothiazol-3-yl)-1 piperazinyl)ethyl)-6-chloro-1,3-dihydro-2(1H)-indol-2-one. 2. The compound of claim 1 in the form of lath crystals. 3. The compound of claim 1 in the form of needle crystals. 4. A pharmaceutical composition for the treatment of a psychotic disorder comprising an amount of the compound of claim 1 that is effective in the treatment of said psychotic disorder and a pharmaceutically acceptable carrier. 5. A method of treating a psychotic disorder in a mammal comprising administering to said mammal an amount of the compound of claim 1 that is effective in the treatment of said psychotic disorder. 6. The method of claim 5 wherein said disorder is schizophrenia, anxiety or migraine pain. 7. The method of claim 5 wherein said disorder is schizophrenia. 8. The method of claim 5 wherein said administration is parenteral administration. 9. The method of claim 8 wherein said parenteral administration is intramuscular injection.
申请公布号 EA001190(B1) 申请公布日期 2000.12.25
申请号 EA19980000912 申请日期 1997.04.10
申请人 PFIZER INC. 发明人 BUSCH, FRANK, ROBERT;SHINE, RUSSELL, JAMES;ROSE, CAROL, ANNE
分类号 A61K31/495;A61K31/496;A61P25/06;A61P25/18;A61P25/22;C07D417/12 主分类号 A61K31/495
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