| 摘要 |
The present invention in all of its associated aspects provides a method for stimulating a systemic immune response in a mammal to a tumor that may be pre-existing, or that may arise following treatment. More particularly, the present invention is concerned with co-administering a tumor cell and a cytokine, the tumor cell expressing at least one cytokine. The invention also relates to a recombinant virus comprising nucleic acid encoding a cytokine, such as human granulocyte-macrophage colony stimulating factor, and tumor cell transduced by such a recombinant virus, wherein the tumor cell expresses human granulocyte-macrophage colony stimulating factor. |
