发明名称 |
USE OF A CYCLOHEXENONE LONG-CHAIN ALCOHOL FOR TREATING NEURODEGENERATIVE DISEASES |
摘要 |
A preventive and therapeutic drug for a neurodegenerative disease containing , as an active ingredient, a cyclohexenone long-chain alcohol compound represented by formula (1) wherein each of R1, R2, and R3 represents a hydrogen atom or a methyl group; and X represents a C10-C28 alkylene group o r alkenylene group. Since the compound of the present invention exhibits excellent neurite-extension ability and an inhibition effect on disorders caused by mutation in an SOD gene, it is useful as the active ingredient of a preventive and therapeutic drug for neurodegenerative diseases, inter alia, amyotrophic lateral sclerosis, and as the active ingredient of an inhibitory drug for disorders caused by mutation in an SOD gene.
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申请公布号 |
CA2360246(A1) |
申请公布日期 |
2000.08.17 |
申请号 |
CA20002360246 |
申请日期 |
2000.02.10 |
申请人 |
MEIJI DAIRIES CORPORATION |
发明人 |
SCHMITT, GABY;LUU, BANG;YAMADA, MASASHI;LOEFFLER, JEAN-PHILIPPE;GONZALEZ DE AGUILAR, JOSE-LUIS;LUTZ-BUCHER, BERNADETTE;CHABERT, PHILIPPE;GIRLANDA-JUNGES, CELINE;KEYLING, FLORENCE;SUMA, YUKIE |
分类号 |
A61K31/12;A61K31/00;A61K31/122;A61P25/00;A61P25/28;A61P43/00;C07C45/51;C07C45/59;C07C45/67;C07C49/713;(IPC1-7):A61K31/122 |
主分类号 |
A61K31/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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