发明名称 CRYTALLINE FORM OF 4-[5-METHYL-3-PHENYLISOXAZOL-4-YL]BENZENESULFONAMIDE
摘要 PURPOSE: A stable crystalline form of 4-£5-methyl-3-phenylisoxazol-4-yl|benzene sulfonamide is provided. The crystal structure, designated Form B, is more stable, has favorable handling properties and is characterized by its melting point, x-ray and other physical characterizations. CONSTITUTION: A pharmaceutical composition comprises a therapeutically-effective amount of crystalline Form B of 4- £5-methyl-3-phenylisoxazol-4-yl)benzene sulfonamide in association with at least one pharmaceutically acceptable carrier, adjuvant or diluent. Wherein, the form of 4-£5-methyl-3-phenylisoxazol-4yl|benzene sulfonamide has a melting point of about 170-174 OC and an IR spectrum with the peaks of 1170, 925, 844, and 729 cm-1.
申请公布号 KR20000029994(A) 申请公布日期 2000.05.25
申请号 KR19997001263 申请日期 1999.02.13
申请人 G.D.SEARLE & CO. 发明人 TALLEY JOHN J;MEDICH JOHN R;MCLAUGHLIN KATHLEEN T.;GAUD HENRY T;YONAN EDWARD E
分类号 A61K31/42;A61P19/02;A61P25/02;A61P29/00;A61P43/00;C07D;C07D261/08;H01L23/40;H01L23/427;(IPC1-7):C07D261/08 主分类号 A61K31/42
代理机构 代理人
主权项
地址