CHIMERIC PROTEINS WITH CELL-TARGETING SPECIFICITY AND APOPTOSIS-DINDUCING ACTIVITIES
摘要
The present invention relates to chimeric proteins with cell-targeting specificity and apoptosis-inducing activities. In particular, the invention is illustrated by a recombinant chimeric protein between human interleukin-2 (IL2) and Bax. The chimeric protein specifically targets IL2 receptor (IL2R)-expressing cells and induces cell-specific apoptosis.
申请公布号
WO9945128(A8)
申请公布日期
1999.11.25
申请号
WO1999IL00120
申请日期
1999.03.02
申请人
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW
发明人
YARKONI, SHAI;AZAR, YEHUDITH;BELOSTOTSKY, RUTH;BEN-YEHUDAH, AHMI;AQEILAN, RAMI, ISHAQ;LORBERBOUM-GALSKI, HAYA
