发明名称 |
PRODUCTION OF MULTIVESICULAR LIPOSOMES |
摘要 |
Multivesicular liposomes are prepared at commercial scales by combining a first w/o emulsion with a second aqueous solution to form a w/o/w emulsion using a static mixer. Solvent is removed from the resulting emulsion to form multivesicular liposome-containing compositions. Further optional process steps include primary filtration and secondary cross-flow filtration. The products produced according to the processes of the invention can be produced through a series of aseptic steps. |
申请公布号 |
CA2309548(A1) |
申请公布日期 |
1999.05.27 |
申请号 |
CA19982309548 |
申请日期 |
1998.11.13 |
申请人 |
SKYEPHARMA INC. |
发明人 |
MEISSNER, DAGMAR;HARTOUNIAN, HARTOUN;PEPPER, CLINT B. |
分类号 |
A61J3/07;A61K9/127 |
主分类号 |
A61J3/07 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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