发明名称 |
Genomic nucleic acids cdna and mrna which code for polypeptides with il-16 activity processes for the production thereof and their use |
摘要 |
A nucleic acid with which expression of a polypeptide having interleukin-16 activity can be achieved or regulated in a prokaryotic or eukaryotic host cell, wherein in the region coding for the polypeptide, the nucleic acid (1) corresponds to the DNA sequence SEQ ID NOS:1 and 5-7 or its complementary strand; (b) hybridizes under stringent conditions with the DNA of sequence SEQ ID NOS:1 and 5-7; (c) or is a nucleic acid sequence which, if there was no degeneracy of the genetic code, would hybridize under stringent conditions with the nucleic acid sequences defined by (a) and (b); (d) and, if it codes for a polypeptide having interleukin-16 activity, is suitable as genomic DNA for the recombinant production of IL-16 in eukaryotic host cells and processes for producing the same and pharmaceutical compositions containing the same. |
申请公布号 |
ZA9703003(B) |
申请公布日期 |
1998.10.23 |
申请号 |
ZA19970003003 |
申请日期 |
1997.04.09 |
申请人 |
BUNDESREPUBLIK DEUTSCHLAND VERTRETREN DURCH DEN BUNDESMINISTER FUER GESUNDHEIT |
发明人 |
REINHARD KURTH;MICHAEL BAIER;NORBERT BANNERT;KARIN METZNER;ALBRECHT WERNER |
分类号 |
C12N15/09;A61K38/00;A61K38/20;A61P31/12;A61P31/18;A61P43/00;C07K14/54;C12N5/10;C12N15/24;C12P21/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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