发明名称 Substituted aminoalkane phosphonic acids
摘要 PCT No. PCT/EP97/05843 Sec. 371 Date Apr. 23, 1999 Sec. 102(e) Date Apr. 23, 1999 PCT Filed Oct. 22, 1997 PCT Pub. No. WO98/17672 PCT Pub. Date Apr. 30, 1998Compounds of the formula I in which R1 is hydroxyl or an aliphatic, araliphatic or aromatic radical, X is a divalent aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, araliphatic, heteroarylaliphatic or aromatic radical, R2 is hydrogen or an aliphatic or araliphatic radical, alk is lower alkylidene and R3, R4 and R5 independently of one another are hydrogen, lower alkyl, halogen, trifluoromethyl, cyano or nitro, and their salts can be used for the treatment of pathological conditions which respond to blockage of excitatory amino acid receptors, and for the production of pharmaceutical preparations.
申请公布号 AU5188598(A) 申请公布日期 1998.05.15
申请号 AU19980051885 申请日期 1997.10.22
申请人 NOVARTIS AG 发明人 PIERRE ACKLIN;HANS ALLGEIER;YVES AUBERSON;DR. SILVIO OFNER;SIEM JACOB VEENSTRA
分类号 A61K31/675;A61P9/00;A61P25/00;A61P25/08;A61P43/00;C07F9/6509 主分类号 A61K31/675
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