摘要 |
<p>A halogen-containing substituted cyclopentene derivative being useful as a novel intermediate for the preparation of prostaglandins useful as drugs and represented by general formula (I) [wherein R is hydrogen, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C7-C19 aralkyl, C6-C12 aryl, C1-C6 alkoxy, C2-C6 alkenyloxy, C1-C6 alkylthio or C2-C6 alkenylthio; X<1> is ( alpha -OZ<a>, beta -H) or ( alpha -H, beta -OZ<a>); X<3> is ( alpha -OZ<d>, beta -H), ( alpha -H, beta -OZ<d>) or oxygen; Z<a> and Z<d> are each independently hydrogen or a hydroxyl-protecting group; and W is halogen], and a process for the preparation of the derivative.</p> |