摘要 |
<p>Novel, biologically active peptides, known as Tryptophyllins L, Rubellidins, Dynastins, Uperins, Eucnemins and Frenatins, and also a new series of Caerin peptides, are extractable from the skin or glands of frogs. These peptides generally have the formula: W-X-Trp-Y-Z, pGlu-X-Trp-Y-Z, W-X-Phe-Phe-Y-Z, W-Gly-Leu-Y-Z, W-Ala-Gly-Y-Z, or W-Gly-Y-Z, wherein W is hydrogen, X and Y are peptide sequences, and Z is hydroxyl or amino. Some of the present peptides have potent physiological activity, e.g. as neurotransmitters, neuromodulators, wide spectrum antibiotics, antiviral agents and nematocidal agents. The peptides may also be used for food preservation.</p> |