摘要 |
Nucleotides conjugated with a chelating agent and labeled with a lanthanide, especially terbium, are readily detected by time-resolved fluorimetry during and following gel electrophoresis. The labeled nucleotide conjugates are very stable, highly fluorescent with a long radiative lifetime and remain fluorescent during dilution and during gel electrophoresis and since an enhancement solution is not required for detection, the labeled nucleotide conjugates can be detectd on-line, if desired. |
申请人 |
THE PERKIN-ELMER CORP., NORWALK, CONN., US |
发明人 |
PICOZZA, ENRICO G., RIDGEFIELD, CT 06877, US;SAAVEDRA, STEVEN S., NEW MILFORD, CT 06776, US |